Radix Stephaniae


The root tuber of Stephania dielsiana, Y.C. Wu, family Menispermaceae.

The mot tuber appearing as irregular masses, 20-30 cm in size. Surface brown, coarse, with spotted rootlet scars. Section whitish and farinaceous. Bitter in taste, cold in nature, slightly toxic and attributive to lung and stomach channels.

1. Remove wind-dampness and relieve pain: For arthralgia of heat type with marked redness, swelling and pain ofjoints.
2. Promote blood circulation to remove blood stasis, clear away toxic material and relieve swelling: For carbuncle, snake bite and trauma.
3. Relax the muscles: As a relaxant for abdominal operation.

Pharmacological Action
1. Its total alkaloid and iodomethyl quatemary ammonium of sinoacutine inhibit the neuromuscular system and relax the striated muscles.
2. Its component stephanine inhibits the growth of sarcoma180 and Werck's carcinoma256 in rats.

Administration Decoction: 3-10g.
Injection (1 ml containing 15 mg of total alkaloid): 0.15-0.4 mi/kg added in 5% glucose 20 ml IV as a muscular relaxant for abdominal operation.


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Mr. Wang Tao

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