Resina Garciniae
Source
The resin of Garcinia morelta Desr., family Guttiferae.
Characteristics
The sample appearing as tubular or irregular masses, red-yellow to orange-brown;
surface with yellow-green powder and longitudinal striae. Fragile in texture.
Section shell-shaped, or with cavea, and waxy luster. Becoming yellow
and milky when ground with water. Inflammable. Sour and astringent in
taste, toxic, and attributive to liver and stomach channels.
Indication
Eliminate toxic material, promote pus drainage and remove blood stasis:
Extemal use for carbuncle, pyogenic infection of skin, ulcera tive gingivitis
and dental caries. Recently, also for carcinoma of breast, cervix and
pancreas and malignant lymphoma.
Pharmacological
Action
1. Morellic acid, one of its components, inhibits Ehrljch-Ascites tumour
and sarcoma180.
2. Inhibiting BEL-7402 species of hepatic cancer cells and HeLa cells
in vitro.
3. Increasing white blood cells and promoting its phagocytosis during
the treatment of cancer in experimental animals.
Administration
Tablet: 60-90mg tid.
Ampoule: 100-200mg added in normal saline 20 ml IV.
5% ointment: For external use.
Caution
Diarrhea, dizziness, thirst, sweating and dryness of nasal cavity may
occur after oral use. Local pain and phlebitis may occur at the site of
injection.