The preparation from arsenolite or arsenide ore, mainly containing arsenic trioxide (As2 03).

The sample appearing as irregular masses, white or pink alternating with yellowish, lustre or lustreless. Brittle in texture. Fracture surface uneven, or appearing as fibrous layers. Acrid and sour in taste, hot in nature, strongly toxic, and attributive to liver and lung channels.

1. Counteract toxic materials, kill microorganism, anticarcinogenic and remove necrotic tissues: External use for superficial tumors such as the cancers of cervix, skin, lips, penis and breast; also for intractable tinea infection, hemorrhoids and ulcers with focal necrosis. Oral administration and intravenous injection for esophageal carcinoma, gastric carcinoma, lymphosarcoma, chronic granulocytic leukemia, etc.
2. Eliminate phlegm, relieve malaria and asthma: For malaria and bronchial asthma of cold-phlegm type.

Pharmacological Action
1. Protoplasmotoxic, inhibiting the activity of mercaptoenzymes and killing tumor cells and other living cells, bactericidal and protozoacidal.
2. Damaging the liver, kidney and capillaries.

Administration Pill and powder:
for killing tumors, 20-30 mg once or twice daily for one to two weeks; 0. l-0.3g for external use daily; for malaria and bronchial asthma, 2-4mg once or thrice daily.
Suppository (composed of aresenicum, alumen, realgar and myrrha):
for carcinoma of cervix as cervical suppository, or prepared as powder externally used for carcinoma of skin.

It is hypertoxic, and high dosage and prolonged use are prohibited. Poisoning may cause vomiting, abdominal pain, diarrhea, hemafecia, tachycardia, dizziness, headache, general aching, or even convulsion, mania, delirium, jaundice, oligouria and shock. Decoctions of Semen Phareoli Radiati, or Rhizoma Smilacis Gkibrae, Flos Lonicerae, Herba Vioiae, Radix Glycyrrhizae may serve as antidotes for mild poisoning, and British antilewisite (BAL) for heavy poisoning.


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Mr. Wang Tao

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