Ramulus et Folium
Cephalotaxi Fortunei


The branch and leaf of Cephalotaxus fortunel Hook. f. family Cephalotaxaceae.

A tree. The branchiets opposite, purple-brown, with long and transverse lenticels. Winter buds tristichous and terminal. Leaves spiral and bifarious; blades linear and lenceolate, midrib evident, with two white stomatic bands on the dorsal side. Bitter and astrirgent in taste, slightly cold in nature, and attributive to liver channel.

Anticarcinogenic: Mainly used for acute non-lymphocytic leukemia such as acute myelocytic leukemia, acute monocytic leukemia, polycythemia vera, erythroleukemia, etc.; also for chronic myelocytic leukemia, malignant lymphoma, etc.

Pharmacological Action
1. Harringtonine, homo-harringtomne, iso-harringtonine and deoxy-harringtonine are the anticarcinogenic components, which interfere the cell growth and mitotic activity, damage and inhibit the growth of S-stage cells and inhibit the synthesis of DNA. Harringtonine and homo-harringtonine are more effective for the interference of mitotic activity.
2. Inhibiting the hematopoietic cells in bone marrow.
3. Causing irritant effect on digestive tract.

Harringtonine injection: 1-6mg added in 5-10% glucose 500 ml IV for drips daily, 5-7 days as one course, 1-3 courses may be applied at an 1-2 weeks intervals; homo-harringtonine, same dosage as harringtonine.


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Mr. Wang Tao

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