The branch and leaf of Cephalotaxus fortunel Hook. f. family Cephalotaxaceae.
A tree. The branchiets opposite, purple-brown, with long and transverse
lenticels. Winter buds tristichous and terminal. Leaves spiral and bifarious;
blades linear and lenceolate, midrib evident, with two white stomatic
bands on the dorsal side. Bitter and astrirgent in taste, slightly cold
in nature, and attributive to liver channel.
Anticarcinogenic: Mainly used for acute non-lymphocytic leukemia such
as acute myelocytic leukemia, acute monocytic leukemia, polycythemia vera,
erythroleukemia, etc.; also for chronic myelocytic leukemia, malignant
1. Harringtonine, homo-harringtomne, iso-harringtonine and deoxy-harringtonine
are the anticarcinogenic components, which interfere the cell growth and
mitotic activity, damage and inhibit the growth of S-stage cells and inhibit
the synthesis of DNA. Harringtonine and homo-harringtonine are more effective
for the interference of mitotic activity.
2. Inhibiting the hematopoietic cells in bone marrow.
3. Causing irritant effect on digestive tract.
Harringtonine injection: 1-6mg added in 5-10% glucose 500 ml IV for drips
daily, 5-7 days as one course, 1-3 courses may be applied at an 1-2 weeks
intervals; homo-harringtonine, same dosage as harringtonine.