Semen Ziziphi Spinosae


Seed of Ziziphus spinosa Hu, family Rhamnaceae.

Seed flat-rounded, 5-9 mm in diameter, 3 mm thick. Spermoderm purple-brown, smooth and bright. A longitudinal stria appearing on one side of the seed, a white linear hilum at one end and a small protruding chalaza at the other end. Sweet and sour in taste, mild in nature, and attributive to heart and liver channels.

1. Nourish the heart, benefit the liver and tranquilize the mind: For deficiency of heart-blood and liver-blood with vexation, insomnia, severe palpitation, frightening and amnesia, used together with Radix Angelicae Sinensis, Radix Polygoni Multiflori and Arillus Longan; for liver-deficiency with heat, used together with Rhizoma Anemarrhenae and Poria; for yin-deficiency with yang-hyperactivity, used together with Radix Rehmanniae and Semen Biotae.
2. Stop sweating: For general debility with spontaneous perspiration, and night sweating.

Pharmacological Action
The chief components are jujuboside A and B.
1. Intraperitoneal injection of its decoction (2.5-5.0g/kg) exerts sedative and hypnotic effects in rats.
2. Intravenous injection of its decoction exerts significant and prolonged hypotensive effect in anesthetized dogs.
3. Occasionally causing heart block.
4. Inducing hysterospasm.

Administration Decoction: 9-18g.


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Mr. Wang Tao

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