Rhizoma Ligustici Chuanxiong

 

Source
The rhizome of Ligusticum chuanxiong Hort., family Umbelliferae.

Characteristics
Rhizome nodular fist-like masses, 1.5-7.0 cm in diameter. Surface yellow-brown, with many and dense stem nodes, protruding, with rounded depressed stem scars on the upper part, and many tubercular root scars on the lower part and nodes. Prepared as crosscutting pieces, margm of the pieces irregularly wavy, grey-yellow. Annular wavy cambium, and brown oily spots scattered. Strongly aromatic in odour. Acrid and bitter in taste, warm in nature, and attributive to liver, gallbladder and pericardium channels.

Indication
1. Promote the circulation of blood and vital energy: For stagnation of blood and vital energy resulting in angina pectoris, headache, chest pain, abdominal pain, dysmenorrhea, amenia, difficult menstruation, dead fetus and retention of placenta, apoplexy, trauma, bony spur, or thromboangiltis obliterans.
2. Expel wind and alleviate pain: For recurrent headache, dizziness, fro headache of wind-cold type and rheumatism. Also used for Leukocytopenia.

Pharmacological Action
1. Its active component, tetramethylpyrazine, can dilate the coronary artery and increase the coronary flow.
2. Its aqueous solution and alcoholic infusion can lower blood pressure.
3. Its alkaloids, ferulic acid and cnidilide are antispasmodics.
4. Inhibiting the growth of intestinal gram-negative bacteria and skin fungi.

Administration Decoction:
3-9g; 9-I 5g for serious cases. Tetramethylpyrazine injection: 40-120 mg added in glucose solution IV in drips daily for angina pectoris and ischemic apoplexy. Sodium ferulate tablet: 10 mg tid for leukocytopenia and pectoris. Powder: External application for bony spur and spinal hyperplasia.


   

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