Radix Sophorae Flavescentis

 

Source
Root of the Sophora flavescens Ait., family Leguminosae.

Characteristics
Root long-terete, with branching roots at the lower part; 10-30 cm long, 1-2 cm in diameter; with transverse and long lenticels on the cork, the peel usually dehiscing and curved outwards or separated. Prepared as crosscut pieces, with bundles radially arranged and cracks on the section, and annual rings visible in the old ones. Bitter in taste, cold in nature, and attributive to heart, liver; stomach, large intestine and urinary bladder channels.

Indication
1. Clear away heat and deprive dampness from middle-jiao: For diarrhea, dysentery, jaundice and leucorrhagia of dampness-heat type. Recently, also used for trichomoniasis intestinalis, lambliasis, trichomonas or mycotic vaginitis (chiefly for local use).
2. Expel wind and kill parasite: For prurigo of wind-heat or dampness-heat type, scabies, pyoderma, leprosy, etc.
3. Eliminate phlegm and relieve dyspnea: For cough and dyspnea.
4. Calm the mind: For insomnia, palpitation, insanity, etc. Recently, used for neurasthenia, manic psychosis and arrhythmia.
5. Clear away heat and promote diuresis: For stranguria of heat type and edema.

Pharmacological Action
1. Matrine and oxymatrine counter the arrhythmia induced by chloroform-adrenaline or aconitine, and its injection slows heart rate and weakens myocardial contractility in experimental animals.
2. Inhibitory on the contraction of sensitized guinea-pig intestine and release of allergic medium in vitro.
3. Antiasthmatic and expectorant.
4. Bacteriostatic, antiamebic and trichomonacidal.
5. Matrine 30 mg/kg and oxymatrine 100 mg/kg on X-ray induced leukopenia in rabbits.
6. Inhibitory on sarcoma180 in mice.

Administration Decoction: 9g: for arrhythmia and psychosis, 30-60g. External use: Appropriate amount.


   

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Mr. Wang Tao

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