Radix Trichosanthis


Root of Trichosanthes kirilowii Maxim., family Cucurbitaceae.

Root irregular long striped or spindle shaped; 8-16 cm long, 1.5-6.0 cm in diameter, yellow-white when the bark separate, with longitudinal striae and long transverse lenticels. Hard in texture. Prepared as crosscut pieces; section showing powdery, vessels or fibres somewhat radial. Sweet and slightly bitter in taste, slightly cold in nature, and attfibutive to lung and stomach channels.

1. Clear away heat and promote the production of fluid: For febrile diseases with thirst or consumption of body fluid, diabetes.
2. Clear away heat and toxic materials, relieve carbuncle and drain the pus: For early stage of skin infection used together with Fructus Forsythiae and Squama Manitis; for abscess, used together with Squama Manitis and Spina Gleditsiae; for ruptured abscess, used together with Radix Astragali seu Hedysari and Radix Glycyrrhizae.
3. Clear away lung-heat and relieve cough: For cough of lung-heat or dryness heat type and hemoptysis.
4. Damage the chorionic syncytial trophoblast: For induction of labour in the second trimester of pregnancy, and trophocytic tumor.

Pharmacologicai Action
1. Interrupting pregnancy.
2. Its active component, trichosanthin, is effective on placental trophocytic tumor.
3. Bacteriostatic.

Administration Decoction:
9-15g. Injection: 10 mg of trichosanthin added in physiological saline 500 ml IV for drips, once 5-7 days after test, used for trophocytic tumor and labour induction.

Intravenous injection may cause fever and allergic reaction, or even allergic shock in severe case, which can be alleviate by preceding use of corticosteroids. Bed rest for 1-2 days is necessary after injection. Contraindicated for those patients suffering from liver, heart and kidney diseases, severe anemia and psychosis.


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Mr. Wang Tao

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