Radix Sophorae Tonkinensis


The root and rhizome of Sophora tonkinensis Chun et T. Chen, family Leguminosae.

Rhizome irregularly nodose, with relic stem bases or traces at the upper part and several terete roots at the lower part, 20-30 cm long, 1.0-1.5 cm in diameter; root cortex with transverse long lenticels. Prepared as segments or pieces. With a smell of beans. Bitter in taste, cold in nature, and attributive to lung channel.

Clear away heat and toxic material, ease the throat: For sore-throat. Recently, also for laryngocarcinoma, early stage of lung cancer, etc.

Pharmacological Action
1. Antineoplastic. Matrine, an active component, is anticarcinogenic on ascitic carcinoma in mice in vitro and in vivo. Other active components, oxymatrine, sophoraponicin, pterorepine, trifolirhizin and maackian, are anticarcinogenic on sarcoma in mice. Its aqueous extract inhibits the growth of cervix carcinoma.
2. Oxymatrine or matrine raise peripheral white cell's level in rabbit.
3. Dauricine relieves arrhythmia induced by aconitine, digitoxin or KC1.
4. Inhibites secretion of gastric juice and promotes the rapair of gastric ulcer.
5. Antiasthmatic.

Administration Decoction: 3-6g.

Caution: Sophora tonkinensis is poisonous and may cause dizziness, nausea and vomiting, so the dose should be limited.


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Mr. Wang Tao

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