Folium Viticis Negundo


Leaf of Vitex negundo L. var. canabifolia (Sieb. et Zucc.) Hand.Mazz, family Verbenaceae.

Leaf palmately compound, with 5 or 3 elliptical leaflets; margin coarsely or shallowly serrate, or entire; green or grey-white on the back. Acrid and bitter in taste, mild in nature, and attributive to lung, stomach and large intestine channels.

I. Expel wind and heat, open the inhibited lung energy and relieve cough: For common cold of wind-heat type, and cough with thick sputum and difficult expectoration.
2. Eliminate dampness from the upper-jiao and regulate the middl~jiqo: For exogenous summer-heat and dampness-syndrome or stagnation of the spleen and stomach with nausea, vomiting, abdominal pain and diarrhea.
3. Expel wind and alleviate itching: External use for skin itching.

Pharmacological Action
1. Oral administration of its emulsion (0.52-1.73g/kg) exerts a strong expectorant effect in mice.
2. Oral administration of its volatile oil (1.04g/kg) exerts a significant antitussive effect in mice with cough induced by inhalation of concentrated ammonia.
3. Increasing the hypnotic effect of pentobarbital sodium in mice.

Administration Decoction: 10-20g.


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