Folium Viticis
Negundo
Source
Leaf of Vitex negundo L. var. canabifolia (Sieb. et Zucc.) Hand.Mazz,
family Verbenaceae.
Characteristics
Leaf palmately compound, with 5 or 3 elliptical leaflets; margin coarsely
or
shallowly serrate, or entire; green or grey-white on the back. Acrid and
bitter in taste, mild in nature, and attributive to lung, stomach and
large intestine channels.
Indication
I. Expel wind and heat, open the inhibited lung energy and relieve cough:
For common cold of wind-heat type, and cough with thick sputum and difficult
expectoration.
2. Eliminate dampness from the upper-jiao and regulate the middl~jiqo:
For exogenous summer-heat and dampness-syndrome or stagnation of 
the
spleen and stomach with nausea, vomiting, abdominal pain and diarrhea.
3. Expel wind and alleviate itching: External use for skin itching.
Pharmacological
Action
1. Oral administration of its emulsion (0.52-1.73g/kg) exerts a strong
expectorant effect in mice.
2. Oral administration of its volatile oil (1.04g/kg) exerts a significant
antitussive effect in mice with cough induced by inhalation of concentrated
ammonia.
3. Increasing the hypnotic effect of pentobarbital sodium in mice.
Administration Decoction: 10-20g.